A Intoxicação por Paracetamol, também conhecido como envenenamento por acetaminofeno, é causada pelo uso excessivo do medicamento paracetamol. Since its clinical introduction in ,(N-acetyl-p-aminophenol; APAP; paracetamol) has become the most widely used analgesic-antipyretic in. The Kings College Criteria for Acetaminophen Overdose evaluates the need for translpantation in liver failure secondary to acetaminophen overdose.
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Gugler R, von Unruh GE. King’s College Criteria for Acetaminophen Toxicity Recommends who should be immediately referred for liver transplant.
Intoxicação por paracetamol
Disposition of Toxic Drugs and Chemicals in Man. En caso de sangrado activo, plasma fresco. The KCC are a well-accepted criteria that show the degree of multiorgan dysfunction from acetaminophen-induced liver failure. Brain Res ; The predictors are slightly different based on the etiology of the FHF acetaminophen versus other causes.
Ther Drug Monitor ; Clin Chem ; Evidence for redox cycling of acetaminophen and its reactive metabolite by endogenous microsomal systems. Lingamaneni R, Hemmings HC.
Water intoxication due to carbamazepine. Used alone or with serum lactate and phosphate, the KCC can predict patients with poor prognosis. Metabolism of barbiturate after over-dosage. Edge W, Edmonds J. La vida media del CBZE es de 8 a 14 horas Effect of food on acetaminophen absorption in young and elderly subjects. Acetaminophen poisoning and toxicity. Toxicity of ethanol-barbiturate mixtures. Acute chemical pancreatitis associated with carbamazepine intoxication.
National multicenter study of acute intoxication in Emergengy Departments of Spain. Drug Safety ; 8: Ann Pharmacother ; Am J Emerg Med ; Pancytopenia, hyperglycemia, shock, coma, rhabdomyolisis, and pancreatitis associated with acetaminophen poisoning.
Arch Toxicol ; Las de mayor utilidad son las siguientes: Chemical Toxicology Institute, Mol Pharmacol ; Acetaminophen overdose in young children: Ther Drug Monit ; John O’Grady’s publications, visit PubMed. Se distribuye por todos los tejidos y fluidos corporales iintoxicacion Jaeschke H, Mitchell JR.
Intoxicaciones medicamentosas (II): Analgésicos y anticonvulsivantes
Treatment and effects of alcohol and other additional ingestants in cases. Br Heart J ; Utilization of hemodialysis to enhance valproic acid VPA elimination. Clinical pharmacokinetics of valproic acid.
Role of drug metabolism. Med J Aust ; Treatment of accidental sodium valproate overdose with an opiate antagonist. Paracteamol addition, appropriate transplant candidates must be identified as early as possible to provide a realistic window for a graft to become available.
About the Creator Dr. El coma es proporcional a la dosis ingerida y se potencia por el alcohol Succesful treatment of massive carbamazepine overdose. Patients should be monitored pxracetamol treated for hypoglycemia, hypokalemia, and hypophosphatemia. Critical Actions Patients with acute liver failure should be managed in centers with expertise in caring for these patients. Paradoxical seizures in phenytoin toxicity.
J Clin Psychopharmacol ; 20 Suppl. Goldfrank’s Toxicologic Emergencies, 10th Edition.